Agomelatine hydrochloride
Product Specifications
CAS Number
1176316-99-6
Synonyms
S-20098 hydrochloride
Target
MT Receptor
Applications
Neuronal Signaling
Molecular Formula
C15H17NO2.ClH
Additionnal Information
Agomelatine hydrochloride (S-20098 hydrochloride) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively. It is also a selective antagonist of 5-HT2C receptors with pKis of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively. Blockade of these receptors enhances adrenergic and dopaminergic transmission in the frontocortical regions.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GA203750 1 Kit
Mouse Calprotectin (S100a8) activation kit by CRISPRa
Sign In for Pricing
View Details