Miglustat hydrochloride
Product Specifications
CAS Number
210110-90-0
Synonyms
N-Butyldeoxynojirimycin hydrochloride, NB-DNJ hydrochloride, OGT 918 hydrochloride
Target
Transferase
Applications
Metabolism
Molecular Formula
C10H21NO4.ClH
Additionnal Information
Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an effective, reversible, and non-toxic iminosugar and an inhibitor of ceramide-specific glucosyl transferase and β-glucosidase 2, with an IC50 of 32 μM and 81 μM, respectively. It is used in the treatment and research of dyslipidosis-related disorders, including GM1 gangliosidosis, Gaucher type I, Tay-Sachs disease, and Niemann-Pick type C disease (NPCD) .
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