Pexidartinib Hydrochloride
Product Specifications
CAS Number
2040295-03-0
Synonyms
PLX-3397 hydrochloride
Target
CSF-1R
Applications
Protein Tyrosine Kinase
Molecular Formula
C20H15ClF3N5.ClH
Additionnal Information
Pexidartinib Hydrochloride is an oral tyrosine kinase inhibitor of colony-stimulating factor 1 receptor (CSF1R) . It significantly reduces macrophage levels in adipose tissue without altering overall myeloid cell counts in mice. It also induces developmental and immunotoxic effects in zebrafish embryos by hyperactivating Wnt signaling.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
131828 100 µg
PRKX (cAMP-dependent Protein Kinase Catalytic Subunit PRKX, PrKX, Protein Kinase X, Protein Kinase X-linked, Serine/Threonine-protein kinase PRKX, Protein Kinase PKX1, PKX1)
Sign In for Pricing
View Details 
GTR15166258 1 Vial
Lentiviral mouse Ptms shRNA (UAS) - Lentiviral mouse Ptms shRNA (UAS, GFP) plasmid
Sign In for Pricing
View Details 
GTR15168391 1 Vial
Lentiviral mouse Hip1 shRNA (UAS) - Lentiviral mouse Hip1 shRNA (UAS) plasmid
Sign In for Pricing
View Details