Deferasirox (Fe3+ chelate)

Deferasirox (Fe3+ chelate) (Exjade) is an oral tridentate iron chelator used for reducing transfusional chronic iron overload. It exhibits efficacy in iron-overloaded patients with anemias, thalassemia, sickle cell disease and myelodysplastic syndromes. It is also an orally effective antitumor agent against solid tumors.