Balinatunfib
Product Specifications
CAS Number
2248726-53-4
Synonyms
SAR441566
Molecular Formula
C27H24F2N6O2
Additionnal Information
Balinatunfib (SAR441566) is an oral inhibitor of tumor necrosis factor receptor 1 (TNFR1) signaling. It binds to the central pocket of the soluble TNFα (sTNFα) trimer, alters its configuration, and prevents heterotrimerization with TNFR1 but not TNFR2, thereby blocking TNFR1 signaling. Balinatunfib exhibits anti-inflammatory activity and has the potential for use in autoimmune disease studies.
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TNF-alpha (APC1, Cachectin, Differentiation inducing factor (DIF), Macrophage cytotoxic factor (MCF), Necrosin, TNF alpha, TNF Macrophage Derived, TNF Monocyte Derived, TNF Superfamily Member 2, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2, Tumor Necrosis Factor Precursor) (BSA & Azide Free) (MaxLight 650)
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