Balinatunfib
Product Specifications
CAS Number
2248726-53-4
Synonyms
SAR441566
Molecular Formula
C27H24F2N6O2
Additionnal Information
Balinatunfib (SAR441566) is an oral inhibitor of tumor necrosis factor receptor 1 (TNFR1) signaling. It binds to the central pocket of the soluble TNFα (sTNFα) trimer, alters its configuration, and prevents heterotrimerization with TNFR1 but not TNFR2, thereby blocking TNFR1 signaling. Balinatunfib exhibits anti-inflammatory activity and has the potential for use in autoimmune disease studies.
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