VLS-1272
Product Specifications
CAS Number
2914878-00-3
Target
Kinesin
Applications
Cytoskeletal Signaling
Molecular Formula
C27H35N3O5S2
Additionnal Information
VLS-1272 is an orally bioavailable, potent, ATP non-competitive, microtubule-dependent, and highly selective inhibitor of KIF18A with an IC50 of 41 nM. It induces mitotic defects with strong anti-mitotic, anti-cancer, and anti-proliferative effects, leading to dose-dependent tumor growth inhibition and can be used for the study of cancers with high chromosomal instability.
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