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PF-07853578

Product Specifications

CAS Number

3036158-98-9

Molecular Formula

C16H19ClF2N2O4S

Additionnal Information

PF-07853578 (Example 11) is a degrader of Patatin-Like Phospholipase Domain-Containing Protein 3 (PNPLA3) with an EC50 of 5.2 nM. It may be useful for the treatment and prevention of liver diseases, including fatty liver, nonalcoholic fatty liver disease (NALFD), nonalcoholic steatohepatitis (NASH), liver fibrosis, cirrhosis, and hepatocellular carcinoma.

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