REM127
Product Specifications
CAS Number
1417823-67-6
Target
Calcium Channel
Applications
Neuronal Signaling
Molecular Formula
C20H20Cl2N4S
Additionnal Information
REM127 is a small molecule that restores calcium homeostasis by stabilizing the septin cytoskeleton, thereby preventing pathological calcium influx in models of tauopathies. It improves synaptic plasticity, reduces tau and Aβ pathology, and rescues memory function in disease models. It exhibits a potential for treating Alzheimer’s disease and frontotemporal dementia.
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