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REM127

Product Specifications

CAS Number

1417823-67-6

Target

Calcium Channel

Applications

Neuronal Signaling

Molecular Formula

C20H20Cl2N4S

Additionnal Information

REM127 is a small molecule that restores calcium homeostasis by stabilizing the septin cytoskeleton, thereby preventing pathological calcium influx in models of tauopathies. It improves synaptic plasticity, reduces tau and Aβ pathology, and rescues memory function in disease models. It exhibits a potential for treating Alzheimer’s disease and frontotemporal dementia.

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