Moracin O

Product Specifications

CAS Number

123702-97-6

Target

HIF

Applications

Angiogenesis

Smiles

CC (O) ([C@H]1CC2=CC (C=C (C3=CC (O) =CC (O) =C3) O4) =C4C=C2O1) C

Molecular Formula

C19H18O5

Additionnal Information

Moracin O is a 2-arylbenzofuran isolated from the Morus alba Linn. Moracin O demonstrates potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1) with an IC50 value of 6.76 nM in a cell-based HRE assay. Moracin O attenuates reactive oxygen species (ROS) generation triggered by oxygen-glucose deprivation (OGD) . Moracin O also exhibits neuroprotective and anti-inflammatory effects.