Osavampator
Product Specifications
CAS Number
1358751-06-0
Synonyms
TAK-653, NBI-1065845
Target
GluR
Applications
Neuronal Signaling
Molecular Formula
C19H23N3O3S
Additionnal Information
Osavampator (TAK-653, NBI-1065845) is a positive allosteric modulator (PAM) of AMPA receptors. It enhances glutamate-induced calcium influx in CHO cells expressing human AMPA receptors with an EC50 of 3.3 μM and potentiates AMPA receptor-mediated currents in rat primary hippocampal neurons with an EC50 of 4.4 μM.
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