INT-767
Product Specifications
CAS Number
1000403-03-1
Target
FXR
Applications
Metabolism
Molecular Formula
C25H44O6S.Na
Additionnal Information
INT-767 is a dual agonist of farnesoid X receptor (FXR) /TGR5 with an EC50 of 0.033 μM and 0.67 μM, respectively. It significantly improves serum liver enzymes, hepatic inflammation, and biliary fibrosis, while inducing bile flow and biliary HCO3− output, making it a promising tool for chronic cholangiopathy research.
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