Chiglitazar (Carfloglitazar)
Product Specifications
CAS Number
743438-45-1
Target
PPAR
Applications
DNA Damage/DNA Repair
Smiles
O=C (C1=CC=C (F) C=C1) C (C=CC=C2) =C2N[C@H] (C (O) =O) CC (C=C3) =CC=C3OCCN4C5=CC=CC=C5C6=CC=CC=C46
Molecular Formula
C36H29FN2O4
Additionnal Information
Chiglitazar (Carfloglitazar) is a potent dual agonist of PPARα and PPARγ with EC50 values of 1.2 μM and 0.08 μM, respectively, and also activates PPARδ with an EC50 of 1.7 μM. It effectively improves insulin resistance and corrects dyslipidemia in monosodium L-glutamate (MSG) -induced obese rats.
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