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GSK-872 hydrochloride

Product Specifications

CAS Number

2703752-81-0

Target

RIP kinase

Applications

Apoptosis

Molecular Formula

C19H17N3O2S2.ClH

Additionnal Information

GSK-872 hydrochloride is an inhibitor of RIPK3, which binds the RIP3 kinase domain with an IC50 of 1.8 nM and inhibits kinase activity with an IC50 of 1.3 nM. It exhibits the potential in alleviating early brain injury by inhibiting neuronal necroptosis and HMGB1-mediated inflammation.

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