OICR-8268
Product Specifications
CAS Number
3000549-26-5
Target
E3 Ligase
Applications
Ubiquitin
Molecular Formula
C19H14Cl2F2N4O2
Additionnal Information
OICR-8268 is a potent, reversible and in-cell active DCAF1 ligand. It significantly binds to DCAF1 WDR domain with an Kd value of 38 nM. It serves as a promising starting point for developing chemical handles for DCAF1-based PROTACs targeting selective protein degradation as well as cancer therapeutics.
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