ATX968
Product Specifications
CAS Number
2973395-71-8
Synonyms
DHX9-IN-2
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Molecular Formula
C18H16ClN3O3S2
Additionnal Information
ATX968 (DHX9-IN-2) is a potent, selective, and orally bioavailable inhibitor of DHX9 helicase with an IC50 of 8 nM. It induces strong and sustained tumor growth inhibition or regression in MSI-H/dMMR colorectal cancer (CRC) xenograft models.
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