KN-93 hydrochloride
Product Specifications
CAS Number
1956426-56-4
Target
CaMK
Applications
Neuronal Signaling
Molecular Formula
C26H29ClN2O4S.ClH
Additionnal Information
KN-93 hydrochloride is a methoxybenzenesulfonamide derivative that inhibits Ca2+/calmodulin-dependent protein kinase II (CaMKII) with a Ki of 0.37 μM. It reduces dopamine (DA) production by influencing the reaction rate of tyrosine hydroxylase (TH), leading to decreased Ca (2+) -mediated phosphorylation of the TH protein.
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