YB-3-17
Product Specifications
CAS Number
2940242-88-4
Target
MTOR
Applications
PI3K/Akt/mTOR
Molecular Formula
C38H39N11O6
Additionnal Information
YB-3−17 is a dual-target compound that effectively and selectively inhibits mTOR with an IC50 of 0.22 nM, while promoting GSPT1 degradation with an IC50 of 5 nM, leading to substantial tumor growth inhibition both in vitro and in vivo. It also exhibits significant antiproliferative activity in glioblastoma models.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
KN200368 1 Kit
elF2 alpha (EIF2S1) Human Gene Knockout Kit (CRISPR)
Sign In for Pricing
View Details 
TRC-P244110-100MG 100 mg
2-Propen-1-yl 2-amino-α-(hydroxyimino)-4-thiazoleacetate
Sign In for Pricing
View Details 
BNC472238-100 1x 100 µL
Ezrin / p81 (CPTC-Ezrin-1), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 