What is the catalog number for JNJ-28583113?

The catalog number for JNJ-28583113 is C03581-5mg.

What sizes are available for JNJ-28583113?

JNJ-28583113 is available in the following size(s): 5 mg.

Is JNJ-28583113 in stock?

JNJ-28583113 is currently made to order / not held in immediate stock. Contact us for lead time.

JNJ-28583113

Product Specifications

CAS Number

2765255-93-2

Target

TRP Channel

Applications

Neuronal Signaling

Molecular Formula

C19H21F3N2O2

Additionnal Information

JNJ-28583113 is a potent, brain-penetrant antagonist of TRPM2 with an IC50 of 126 nM that protects cells from oxidative stress-induced death and morphological changes. It also inhibits microglial cytokine release in response to pro-inflammatory stimuli and promotes GSK3α/β phosphorylation.