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Ro 67-7476

Product Specifications

CAS Number

298690-60-5

Additionnal Information

Ro 67-7476 is a potent positive allosteric modulator of mGluR1 and potentiates glutamate-induced calcium release in HEK293 cells expressing rat mGluR1a with an EC50 of 60.1 nM. Ro 67-7476 is a potent P-ERK1/2 agonist?and activates ERK1/2 phosphorylation in the absence of exogenously added glutamate (EC50=163.3 nM) .

Storage Conditions

3 years-20°C powder 2 years-80°C in solvent

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