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Gliocidin

Product Specifications

CAS Number

62289-81-0

Synonyms

SW106065

Target

Dehydrogenase

Applications

Metabolism

Molecular Formula

C10H8N2OS

Additionnal Information

Gliocidin (SW106065), is a nicotinamide-mimetic prodrug that targets glioblastoma cells with an IC50 of 150 nM, by exploiting a de novo purine synthesis vulnerability via indirect inhibition of IMPDH2. It readily crosses the BBB and can be used in the treatment of all malignant brain tumors.

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