Gliocidin
Product Specifications
CAS Number
62289-81-0
Synonyms
SW106065
Target
Dehydrogenase
Applications
Metabolism
Molecular Formula
C10H8N2OS
Additionnal Information
Gliocidin (SW106065), is a nicotinamide-mimetic prodrug that targets glioblastoma cells with an IC50 of 150 nM, by exploiting a de novo purine synthesis vulnerability via indirect inhibition of IMPDH2. It readily crosses the BBB and can be used in the treatment of all malignant brain tumors.
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