GLPG3312
Product Specifications
CAS Number
2340388-72-7
Target
SIK
Applications
Immunology & Inflammation
Molecular Formula
C23H21F2N5O3
Additionnal Information
GLPG3312 is a potent and selective inhibitor of pan-SIK, with an IC50 of 2.0 nM for SIK1, 0.7 nM for SIK2, and 0.6 nM for SIK3. It demonstrates anti-inflammatory and immunoregulatory activities in vitro in human primary myeloid cells and in vivo in mouse models.
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