Exatecan
Product Specifications
CAS Number
171335-80-1
Synonyms
DX-8951
Target
Topoisomerase
Applications
DNA Damage/DNA Repair
Molecular Formula
C24H22FN3O4
Additionnal Information
Exatecan (DX-8951), is a water-soluble derivative of camptothecin. It acts as an inhibitor of DNA topoisomerase I with an IC50 value of 1.906 μM. It demonstrates potent antitumor effects and triggers apoptotic cell death after treatment in human pancreatic cancer cells.
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