DC-Y13-27
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DC-Y13-27, a derivative of DC-Y13, is an inhibitor of YTHDF2 with a KD of 37.9 μM. It also upregulates FOXO3 and TIMP1 while downregulating MMP1, MMP3, MMP7, and MMP9. Additionally, it enhances the antitumor effects of radiotherapy and radio-immunotherapy and is implicated in intervertebral disc degeneration pathogenesis research.
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