Cariprazine
Product Specifications
CAS Number
839712-12-8
Synonyms
RGH-188, MP-214
Target
Dopamine Receptor
Applications
Neuronal Signaling
Molecular Formula
C21H32Cl2N4O
Additionnal Information
Cariprazine (RGH-188, MP-214) acts primarily as a partial agonist at dopamine receptors, with pKi values of 10.07 for D3, 9.16 for D2L, and 9.31 for D2S receptors. It also acts as an antagonist forserotonin receptors, with pKi of 9.24, 8.59, 7.73, and 6.87 for5-HT2B,5-HT1A, 5-HT2A, and 5-HT2C receptors, respectively.
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