Dacomitinib hydrate
Product Specifications
CAS Number
1042385-75-0
Synonyms
PF-00299804, PF-804
Target
EGFR
Applications
Protein Tyrosine Kinase
Molecular Formula
C24H25ClFN5O2.H2O
Additionnal Information
Dacomitinib hydrate (PF-00299804, PF-804) is an orally administered, highly selective irreversible inhibitor targeting pan-ERBB receptors, with an IC50 of 6.0 nM for EGFR, 45.7 nM for ERBB2, and 73.7 nM for ERBB4. It also demonstrates anti-tumor activity.
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