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Estramustine

Product Specifications

CAS Number

2998-57-4

Synonyms

NSC-89201, LEO275

Target

Microtubule Associated

Applications

Cytoskeletal Signaling

Molecular Formula

C23H31Cl2NO3

Additionnal Information

Estramustine (NSC-89201, LEO275) is used to treat hormone-resistant prostate cancer and stabilize microtubule dynamics. It acts as an anti-mitotic and anti-microtubule agent and disrupts microtubule disassembly. It inhibits the binding of MAPs 1 and 2 to taxol-stabilized microtubules, hinders microtubule assembly, and promotes the disassembly of MAP-2-associated microtubules.

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