Lodoxamide
Product Specifications
CAS Number
53882-12-5
Synonyms
U-42585E free acid
Target
GPR
Applications
GPCR & G Protein
Molecular Formula
C11H6ClN3O6
Additionnal Information
Lodoxamide (U-42585E free acid) is a potent agonist of GPR35 with an EC50 of 1 nM. It also inhibits eosinophil peroxidase release after IgA activation and reduces eosinophil cationic protein and eosinophil-derived neurotoxin, suggesting direct effects on eosinophils. It is a mast cell stabilizer used to treat asthma, allergic conjunctivitis, and superior limbic keratoconjunctivitis.
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