Mebhydroline
Product Specifications
CAS Number
524-81-2
Target
FXR
Applications
Metabolism
Molecular Formula
C19H20N2
Additionnal Information
Mebhydroline acts as a selective antagonist of farnesoid X receptor (FXR) . Mebhydrolin improves blood glucose balance in in vivo mice models by inhibiting hepatic gluconeogenesis through the FXR/miR-22-3p/PI3K/AKT/FoxO1 pathway and enhancing glycogen synthesis. It also acts as a specific antagonist of histamine H1 receptor. It has potential for its use in the treatment of Type 2 diabetes mellitus (T2DM) .
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