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Mebhydroline

Product Specifications

CAS Number

524-81-2

Target

FXR

Applications

Metabolism

Molecular Formula

C19H20N2

Additionnal Information

Mebhydroline acts as a selective antagonist of farnesoid X receptor (FXR) . Mebhydrolin improves blood glucose balance in in vivo mice models by inhibiting hepatic gluconeogenesis through the FXR/miR-22-3p/PI3K/AKT/FoxO1 pathway and enhancing glycogen synthesis. It also acts as a specific antagonist of histamine H1 receptor. It has potential for its use in the treatment of Type 2 diabetes mellitus (T2DM) .

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