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Tafamidis meglumine

Product Specifications

CAS Number

951395-08-7

Synonyms

Vyndaqel, Fx-1006A

Target

Others

Applications

Others

Molecular Formula

C14H7Cl2NO3.C7H17NO5

Additionnal Information

Tafamidis meglumine (Vyndaqel, Fx-1006A) stabilizes the tetrameric structure of transthyretin (TTR) by binding to thyroxine-binding sites. Tafamidis meglumine treats transthyretin familial amyloid polyneuropathies (TTR-FAP), a condition characterized by neurological damage from TTR amyloidosis, by preventing the misfolding and aggregation of transthyretin (TTR) into amyloid fibrils.

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