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Tazemetostat hydrobromide

Product Specifications

CAS Number

1467052-75-0

Synonyms

EPZ-6438 hydrobromide

Target

EZH1/2

Applications

Epigenetics

Molecular Formula

C34H44N4O4.BrH

Additionnal Information

Tazemetostat hydrobromide (EPZ-6438 hydrobromide) is a potent, selective, and orally available inhibitor of EZH2. It inhibits EZH2 with IC50 values of 11 and 16 nM in peptide assay and nucleosome assay, respectively. Tazemetostat hydrobromide also inhibits EZH1 with an IC50 of 392 nM.

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