Tacrine
Product Specifications
CAS Number
321-64-2
Target
AChR
Applications
Neuronal Signaling
Molecular Formula
C13H14N2
Additionnal Information
Tacrine is a potent acetylcholinesterase (AChE) inhibitor. It inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with an IC50 of 77 nM and 69 nM, respectively. It is used in the treatment of Alzheimer's disease (AD), also poisoning topoisomerases and inhibiting in vivo (mitochondrial) mtDNA synthesis.
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