Adezmapimod hydrochloride
Product Specifications
CAS Number
869185-85-3
Synonyms
RWJ 64809 hydrochloride, SB 203580 hydrochloride
Target
P38 MAPK
Applications
MAPK
Molecular Formula
C21H16FN3OS.ClH
Additionnal Information
Adezmapimod hydrochloride (RWJ 64809 hydrochloride, SB 203580 hydrochloride) is an inhibitor of the MAPK family member termed as stress-activated protein kinase 2a (SAPK2a; also known as p38) . It exhibits IC50 of SAPK2a/p38 and SAPK2b/p38β2 with IC50 values of 50 nM and 500 nM respectively and can be used in research of chronic inflammatory diseases, such as rheumatoid arthritis.
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