Nigericin
Product Specifications
CAS Number
28380-24-7
Target
Potassium Channel
Applications
Transmembrane Transporters
Molecular Formula
C40H68O11
Additionnal Information
Nigericin is an antibiotic derived from Streptomyces hygroscopicus that acts as a K+/H+ ionophore, which causes the efflux of potassium from the cell and, thus, influences the mitochondria membrane potential. It also induces pyroptosis in macrophages by activating NLRP3 inflammasome.
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