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Nigericin

Product Specifications

CAS Number

28380-24-7

Target

Potassium Channel

Applications

Transmembrane Transporters

Molecular Formula

C40H68O11

Additionnal Information

Nigericin is an antibiotic derived from Streptomyces hygroscopicus that acts as a K+/H+ ionophore, which causes the efflux of potassium from the cell and, thus, influences the mitochondria membrane potential. It also induces pyroptosis in macrophages by activating NLRP3 inflammasome.

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