STL127705
Product Specifications
CAS Number
1326852-06-5
Molecular Formula
C22H20FN5O4
Additionnal Information
STL127705 is a potent small molecule inhibitor of Ku70/80 heterodimer protein with an IC50 of 3.5 μM. It disrupts Non-Homologous End-Joining (NHEJ) by preventing DNA binding and inhibiting DNA-PKCS activation. It exhibits anticancer activity by inducing apoptosis and inhibiting cell proliferation.
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