Semustine
Product Specifications
CAS Number
13909-09-6
Target
DNA alkylator
Applications
DNA Damage/DNA Repair
Molecular Formula
C10H18ClN3O2
Additionnal Information
Semustine is a member of the chloroethyl nitrosourea (CENU) family that induces DNA alkylation at the major groove, forming interstrand cross-links between guanine and cytosine bases (dG-dC) . It exerts antitumor activity by inducing these DNA cross-links and is used as an antineoplastic alkylating agent for treating Lewis lung carcinoma, leukemia, and metastatic brain tumors.
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb1725575-01 50 µL
Phospho-beta Catenin (Ser37) polyclonal antibody
Sign In for Pricing
View Details orb1725575-02 100 µL
Phospho-beta Catenin (Ser37) polyclonal antibody
Sign In for Pricing
View Details 
NBP2-89344FR 0.1 mL
Rabbit Monoclonal Complement Component C1s Antibody (006) [DyLight 680]
Sign In for Pricing
View Details