NNK
Product Specifications
CAS Number
64091-91-4
Molecular Formula
C10H13N3O2
Additionnal Information
NNK is a potent carcinogen formed by nitrosation of nicotine that promotes survival and proliferation of human lung cancer cells. It activates ERK1/2 and PKCα, leading to Bcl2 and c-Myc phosphorylation, which may contribute to lung cancer development and chemoresistance and can be used for lung cancer mice model structure.
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