Cpd. 37
Product Specifications
CAS Number
3042878-82-7
Synonyms
MYC-IN-3
Target
Myc
Applications
Apoptosis
Molecular Formula
C25H20ClF6N3O2
Additionnal Information
MYC-IN-3 (Cpd. 37) is an alkynyl-substituted phenylpyrazole derivative and an inhibitor of MYC function by disrupting MYC/MAX interaction with an IC50 of 1.27 μM in PC3 cells and preventing MYC/MAX binding to DNA. It exhibits antiproliferative activity against multiple malignant cell lines and demonstrates enhanced therapeutic efficacy in a mouse allograft model of prostate cancer.
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