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Cpd. 37

Product Specifications

CAS Number

3042878-82-7

Synonyms

MYC-IN-3

Target

Myc

Applications

Apoptosis

Molecular Formula

C25H20ClF6N3O2

Additionnal Information

MYC-IN-3 (Cpd. 37) is an alkynyl-substituted phenylpyrazole derivative and an inhibitor of MYC function by disrupting MYC/MAX interaction with an IC50 of 1.27 μM in PC3 cells and preventing MYC/MAX binding to DNA. It exhibits antiproliferative activity against multiple malignant cell lines and demonstrates enhanced therapeutic efficacy in a mouse allograft model of prostate cancer.

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