TYRA-300
Product Specifications
CAS Number
2800223-30-5
Target
FGFR
Applications
Protein Tyrosine Kinase
Molecular Formula
C25H24Cl2N6O3S
Additionnal Information
TYRA-300 , a 3-pyridylindazole analog, is a reversible and selective inhibitor of FGFR3 with an IC50 of 11 nM in Ba/F3 cells. It also exhibit potent activity in human bladder cancer cell lines harboring FGFR3 activating fusions or mutations.
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