SDU-071
Product Specifications
CAS Number
3036109-10-8
Target
Epigenetic Reader Domain
Applications
Epigenetics
Molecular Formula
C28H25N3O2
Additionnal Information
SDU-071 is an inhibitor of BRD4-p53 protein-protein interaction with IC50 of 2.7 μM, which suppresses MDA-MB-231 triple-negative breast cancer (TNBC) cell migration, invasion, and in vivo tumor growth. It also exhibits antiproliferative activity in concentration concentration-dependent manner, with IC50 of 10.5 μM (72 h) and 12.6 μM (96 h) in MDA-MB-231 cells.
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