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EZH2/HSP90-IN-29

Product Specifications

CAS Number

3033571-35-3

Target

EZH1/2

Applications

Epigenetics

Molecular Formula

C40H48N4O6

Additionnal Information

EZH2/HSP90-IN-29 is a potent dual inhibitor of EZH2 and HSP90, with IC50s of 6.29 nM and 60.1 nM, for EZH2 and HSP90, respectively, that induces M-phase cell cycle arrest, promotes apoptosis/necrosis-related gene expression, and inhibits ROS catabolism. It crosses the blood-brain barrier and can show potential as a tractable anti-GBM agent for glioblastoma research.

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