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PKUMDL-LC-101-D04

Product Specifications

CAS Number

2143896-83-5

Synonyms

GPX4-Activator-1d4

Target

Peroxidases

Applications

Metabolism

Molecular Formula

C14H22N4O2S2.ClH

Additionnal Information

PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a potent allosteric activator of Glutathione peroxidase 4 (GPX4) effectively suppressing ferroptosis and inflammation. It enhances GPX4 activity by 150% at 20 μM in a cell-free assay and 61 μM in cell extracts, also providing protection against cholesterol hydroperoxide (ChOOH) -induced damage.

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