KT-413
Product Specifications
CAS Number
2655656-99-6
Synonyms
IRAK degrader-1, zomiradomide
Target
IRAK
Applications
Immunology & Inflammation
Molecular Formula
C45H48F3N7O6S
Additionnal Information
KT-413 (IRAK degrader-1, zomiradomide) is a dual-function PROTAC molecule and a potent degrader of interleukin-1 receptor associated kinase 4 (IRAK4) and the transcription factors Ikaros and Aiolos by acting as both a heterobifunctional degrader and a molecular glue. It can be used in research for developing therapies targeting the activated B-cell (ABC) subtype of diffuse large B-cell lymphoma (DLBCL) .
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