Pico145
Product Specifications
CAS Number
1628287-16-0
Synonyms
HC-608
Target
TRP Channel
Applications
Neuronal Signaling
Molecular Formula
C23H20ClF3N4O5
Additionnal Information
Pico145 (HC-608) is a selective inhibitor of TRPC1/4/5 channels. It inhibits (−) -englerin A-activated TRPC4/TRPC5 channels, with IC50 values of 0.349 and 1.3 nM, respectively. It exhibits no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8.
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