Taminadenant
Product Specifications
CAS Number
1337962-47-6
Synonyms
NIR178, PBF509
Target
Adenosine Receptor
Applications
GPCR & G Protein
Molecular Formula
C10H8BrN7
Additionnal Information
Taminadenant (NIR178, PBF509) is a non-xanthine and non-furan antagonist of adenosine A2A receptor (A2AR) . It can antagonize A2AR agonist-mediated cAMP accumulation and impedance responses with Kb values of 72.8 nM and 8.2 nM, respectively. It exhibits potential utility for Parkinson’s disease (PD) treatment.
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